HEALTH CABINET

A comprehensive list of prescription and over the counter medications.

XIAFLEX

Xiaflex is a medication that uses enzymes to break down collagen, a tough and strong substance that causes symptoms in a variety of different diseases.

Warnings & Precautions

Treatments for certain penis conditions can cause serious injury. Before use, talk to your doctor and pharmacist about any collagen allergies or other allergies to medications. You may be exposed to an allergic attack from other ingredients used. Also, talk with your doctor about medical history if you have experience bleeding/clotting problems. It is unknown if this medication is passed through breast milk.

Uses

Xiaflex has been approved for use to treat disorders caused by a collagen protein in your body. These disorders include Dupurtren's contracture and Peyronie's disease. Collagen can be found in the knots/cords of the hands in Depurten's contracture and in the penis in Peyronie's disease. The enzymes in this medication breakdown the collagen to help treat the diseases.

The medication is injected into the collagen problem areas and the injected site is wrapped in soft gauze after the medication is administered. You do not move the hand for the hours after the injection and must keep it elevated. You must also do a follow up visit with your doctor 24 hours after the injection. You must also wear a splint for up to 4 months.

If for use to treat Peyronie's disease, the medication is injected into the affected tissue of the penis. Two injections are done at each treatment and there are two injection treatments 1-2 days apart. A straightening procedure is then done one to three days after the second injection.

Side Effects

If you experience numbness, tingling, or a "pins and needles" feeling contact your doctor immediately.

If you notice severe bruising or swelling of the penis, contact your doctor immediately. Common side effects include swelling, bruising, redness, itching or potential bleeding around the injection site. Swollen lymph nodes may also occur in the underarm and elbow when injected into the hand. If these effects do not clear up, contact your doctor.

Also, watch for signs of infection, pain in the ligaments, signs of nerve injury or difficulty moving your fingers. Serious side effects are rare, but if you experience any of them call your doctor immediately.

Interactions

Drug interactions can change how the medication works and increase your risk for serious side effects. Before starting treatment, share a current medication list with your doctor and pharmacists to check for potential drug interactions. Blood thinners and some over the counter drugs (like aspirin and ibuprofen) can cause drug reactions.

Overdose

If you miss a dose, contact your doctor immediately to establish a new dosing schedule. Since this medication is an injection, you will not store it at home.


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